This can be shown in a LOW LEVEL COMPLEX sample analysis, like a dilute fraction from a whole cell lysate digestion for instance. With ABIRD on, more PSMs were found, and at a lower signal level (blue bars) than with ABIRD off (red bars). This is 14 runs from a single vial with ABIRD alternating between on and off.
Can you do this? Probably not at first, many lab dependent factors are involved. This is actually a subtle difference between data sets, only 10% more PSMs with ABIRD. But see the intensity difference of the PSMs, and correlate how that would improve an even more complex low level data set.